Cases / 2025-08-01-D-1213
discontinued2025-08-01D series

Deutivacaftor/Tezacaftor/Vanzacaftor

Zystische Fibrose, mindestens eine Nicht-Klasse-I-Mutation, ≥ 6 Jahre

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Brand
Alyftrek
Manufacturer
Vertex Pharmaceuticals (Germany) GmbH

G-BA action

discontinuation

2026-01-22

Arzneimittel-Richtlinie/Anlage XII: Deutivacaftor/Tezacaftor/Vanzacaftor (Zystische Fibrose, mindestens eine Nicht-Klasse-I-Mutation, ≥ 6 Jahre) – Einstellung eines Verfahrens zur Nutzenbewertung

Evidence-checked summary

The G-BA issued a discontinuation on 2026-01-22. The official page states that it took effect as follows: 22.01.2026. The page lists Arzneimittel-Richtlinie, Anlage XII: Nutzenbewertung nach § 35a SGB V as the normative target.

This is the latest validated public action attached to this case. It is separate from the IQWiG assessment result.

Official case record

What happened, in source order

No inferred stages

Consultation record

Oral hearing and Wortprotokoll

1 hearing

2025-12-08

87 parsed turns

Oral hearing: Deutivacaftor/Tezacaftor/Vanzacaftor (Zystische Fibrose, mindestens eine Nicht-Klasse-I-Mutation, ≥ 6 Jahre)

Official Wortprotokoll · 11 pages

IQWiG comparison

Assessment record versus G-BA action

0 reference

IQWiG assessment findings and the later G-BA action are separate records. Open both to compare them.

No IQWiG assessment reference is present on the validated official case page. This is an explicit absence, not a broken graph link.

G-BA decisions

Distinct actions and documents

1 decision

2026-01-22

discontinuation

Arzneimittel-Richtlinie/Anlage XII: Deutivacaftor/Tezacaftor/Vanzacaftor (Zystische Fibrose, mindestens eine Nicht-Klasse-I-Mutation, ≥ 6 Jahre) – Einstellung eines Verfahrens zur Nutzenbewertung

The G-BA issued a discontinuation on 2026-01-22. The official page states that it took effect as follows: 22.01.2026. The page lists Arzneimittel-Richtlinie, Anlage XII: Nutzenbewertung nach § 35a SGB V as the normative target.

2 official documents · 3 cited claims

Official sources

Case document package

6 source
Generic graph relations · 4